Snapshots of Pluripotency

Snapshots of Pluripotency

Pluripotency is a unique developmental state that lays the foundation upon which the entire embryo is built. Pluripotent cells possess the unique capacity to generate, in an exquisitely defined sequence, all the distinct cell types comprising the fetal and adult organism. The discovery of pluripotent stem cells and now the ability to generate them from differentiated cells has had a profound im...

Snapshots.

Lazy Snapshots

Determining the global state of distributed systems is an important problem in the absence of global memory and global clocks. Several algorithms have been proposed for collecting global states. This paper presents an optimization to the algorithm proposed by Chandy and Lamport that lets processes in a distributed system take a lazy approach to recording their state. The lazy optimization relax...

Snapshots of cytochrome c folding.

Dansyl-to-heme distance distributions [P(r)] during folding have been determined in five variants of Saccharomyces cerevisiae iso-1 ferricytochrome c (labeled at mutant Cys residues 4, 39, 50, 66, and 99) by analysis of fluorescence energy-transfer kinetics. Moment analysis of the P(r) distributions clearly indicates that cytochrome c refolding is not a simple two-state process. After 1 ms of f...

Personal Constructions of Holiday Snapshots